OBUS FORME
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W down cell division or cause cells to die at the appropriate time are called tumor suppressor genes. Cancers can be caused by dna changes that turn on oncogenes or turn off tumor suppressor genes. People inherit 2 copies of each gene – one from each parent. People can inherit damaged dna from one or both parents, which accounts for inherited cancers. Most cancers, though, are not inherited. In these cases, a person's dna is damaged by exposure to something in the environment, like smoking or radiation. Other dna changes may just be random events that sometimes happen inside a cell, without having an external cause. Papillary thyroid cancer several dna mutations have been found in some forms of papillary thyroid cancer. viagra without a doctor prescription viagra generic for sale viagra without a doctor prescription cheap viagra cheap generic viagra buy viagra online buy viagra online usa buy cheap viagra generic viagra online buy viagra Many of these cancers have changes in specific parts of the ret gene. The altered form of this gene, known as the ptc oncogene, is found in about 10% to 30% of papillary thyroid cancers overall, and in a larger percentage of these cancers found in children and/or linked with radiation exposure. These ret mutations usually are acquired during a person's lifetime rather than being inherited. They are present only in cancer cells and are not passed on to the patient's children. Many (30% to 70%) papillary thyroid cancers contain a mutation of the braf gene. The braf mutation is less common in thyroid cancers in children and in those thought to arise from exposure to radiation. Cancers with braf changes tend to have more aggressive growth and a greater likelihood of spreading to other parts of the body. Both braf and ret/ptc changes are thought to cause cells to grow and divide. It is extremely rare for papillary cancers to have changes in both the braf and ret/ptc genes. Some doctors now advise testing papillary cancer samples for these gene mutations, as some studies have suggested they may affect a person's prognosis (outlook). Changes to other genes have also been tied to papillary thyroid cancer, including those in the ntrk1 gene and the met gene. Follicular thyroid cancer acquired changes in the ras oncogene have a role in causing some follicular thyroid cancers. Anaplastic thyroid cancer these cancers tend to have some of the mutations described above and often have changes in the p53 tumor suppressor gene and the ctnnb1 oncogen. Print this pageAdd to Favorite
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